It girl Serena van der Woodsen has returned to Manhattan after a mysterious and self-imposed exile to boarding school. Serenas best friend, Blair Waldorf, has conflicted feelings about her friends return since she has enjoyed being the Queen Bee during Serenas absence and might not be ready to relinquish her new position on the social ladder, not to mention the fact that she has always suspected there may be unspoken feelings between Serena and her longtime boyfriend, Nate.